Editorial


Cholangiocarcinoma: Challenges and future needs

Laura Tariciotti, Ilaria Lenci, Leonardo Baiocchi

Abstract

Cholangiocarcinoma (CCA) is a malignant neoplasm that
arises from the biliary tract epithelia. CCA is the second most
common primary liver tumour after hepatocellular carcinoma,
representing 10-25% of primary hepatic malignancies (1).
CCA is rare in many parts of the world, such as Europe and
the United States (US), accounting for <3% of all malignant
tumours. However, there is a dramatic geographic variation in its
incidence, which reflects regional differences in risk factors and
epidemiology (2,3).