@article{TGC2860,
author = {Felipe Osório-Costa and José B. C. Carvalheira},
title = {TNF-α in obesity-associated colon cancer},
journal = {Translational Gastrointestinal Cancer},
volume = {2},
number = {4},
year = {2013},
keywords = {},
abstract = {Obesity is leading to an unparalleled increase in the incidence of metabolic diseases and cancers, including colon cancer. Research over the last few decades revealed obesity as a low-grade chronic inflammatory state, which has recently been implicated in colon carcinogenesis. Understanding the molecular links of obesity-associated inflammation with colon carcinogenesis is therefore more critical than ever. In this review we discuss the central role of TNF-α, the prototypical pro-inflammatory cytokine, in the pathophysiology of obesity-associated colon carcinogenesis.},
url = {https://tgc.amegroups.com/article/view/2860}
}