%0 Journal Article
%T Non-coding RNAs in human liver malignancies: Critical regulators for cancer stemness?
%A Meng, Fanyin
%A Francis, Heather
%A Alpini, Gianfranco
%J Translational Gastrointestinal Cancer
%D 2012
%B 2012
%9 
%! Non-coding RNAs in human liver malignancies: Critical regulators for cancer stemness?
%K 
%X Cancer stem cells (CSCs) have become one of the essential  topics in cancer research over the past few years (1). Present  chemotherapy modalities eliminate the bulk of the tumor cells,  but cannot eliminate a core of these CSCs that have a high  capacity for renewal. Identification of these cells is the first step  in the development of therapeutic modalities (2). CSCs have  been defined as a unique subpopulation in tumors that have the  capacity to initiate tumor growth and sustain tumor self-renewal.  Although evidence has been provided to support the existence of  CSCs in various solid tumors, the identity and functions of liver  CSCs remains unclear.
%U https://tgc.amegroups.com/article/view/547
%V 1
%N 1
%P 1-4