AB19. Clinical analysis of locally advanced gastric cancer with combined multiorgan resection (93 cases report)
Abstract

AB19. Clinical analysis of locally advanced gastric cancer with combined multiorgan resection (93 cases report)

Chao-Hui Zuo1, Li Zhang1, Yong-Zhong Ou yang 1, Ming Tan1, Hua Xiao1, Xiao-Xin Qiu1, Jin-Guan Lin1, Shu-Gung Pang1, Bing Yin1, Wei Luo1, Sheng-Chuan Mo1, Hai-Zhen Zhu2

1Department of Gastroduodenal and Pancreatic Surgery, Hunan Province Tumor Hospital/Affiliated Tumor Hospital of Xiangya College, Central South University, Changsha, 410013, China;2Liver Cancer Translational Medicine Center of Hunan University and Affiliated Tumor Hospital of Xiangya College, Changsha 410082, China

Objective: To investigate the surgical methods of advanced gastric cancer with combined multiorgan resection and its prognosis.

Methods: The clinical data of 93 patients underwent multiorgan resection for locally advanced gastric cancer admitted from January 2002 to December 2009 were analyzed retrospectively. The postoperative morbidity, the mortality and the overall survival rates were evaluated.

Results: 93 patients underwent multiorgan resection, 24 cases with splienectomy plus distal pancreatectomy, 17 cases with splenectomy, 10 cases with transverse colotectomy, 10 cases with left hepatectomy, 7 cases with cholecysteetomy, 5 cases with diaphragmatictectomy, 5 cases with splienectomy, 5 cases distal pancreatectomy plus transverse colotectomy, 5 cases with double oopherectomy, 4 cases with left hepatectomy plus transverse colotectomy, 3 cases with pancreatoduodenectomy, 2 cases with auxiliary adrenalectomy, 1 cases with distal pancreatectomy, splienectomy, left hepatectomy, diaphragmatictectomy plus auxiliary adrenalectomy. The postoperative morbidity and mortality rates were 31.18% (29/93) and 4.30% (4/93), respectively. The 1-year and 3-year overall survival rates were 50.11% and 26.12%, respectively.

Conclusions: Combined multiorgan resection is worthwhile and highly effective with careful patient selection for locally advanced gastric cancer. Preoperative neoadjuvant chemotherapy improve survival resection rates, and Intraoperative intrapeitoneal hyperthermic chemotherapy using sustained-release fluorouracil is highly effective comprehensive treatment method.

Keywords: Advanced gastric cancer; multiorgan resection; neoadjuvant chemotherapy; intraperitoneal hyperthermic chemotherapy

Cite this abstract as: Zuo CH, Zhang L, Ou yang YZ, Tan M, Xiao H, Qiu XX, Lin JG, Pang SG, Yin B, Luo W, Mo SC, Zhu HZ. Transl Gastrointest Cancer 2013;2(S1):AB19. doi: 10.3978/j.issn.2224-4778.2013.s019