AB54. Value of multidetector-row CT in the preoperative staging of gastric cancer: a single-center and large-scale study
Abstract

AB54. Value of multidetector-row CT in the preoperative staging of gastric cancer: a single-center and large-scale study

Chao Yan1, Zheng-Gang Zhu1, Min Yan1, Jun Chen1, Ming Xiang1, Ming-Min Chen1, Huan Zhang2, Bing-Ya Liu1, Yan-Zhen Lin1

1Department of General Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025, China;2Department of Radiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China

Objective: To investigate the value of multidetector-row CT (MDCT) in the preoperative staging of gastric cancer.

Methods: 1,131 gastric cancer patients underwent preoperative MDCT examination, and the results of MDCT were compared with surgical and pathological findings.

Results: The overall accuracy of MDCT in determining the T stage of gastric cancer was 75.3% (T1 74.3%, T2-3 42.9%, T4a 85.6%, T4b 81.9%). The overall diagnostic sensitivity, specificity, positive predictive value, negative predivtive value, and accuracy of MDCT for determining lymph node metastasis was 83.3%, 71.8%, 81.2%, 74.6%, and 78.6% respectively; while those for determining distant metastasis was 70.4%, 98.3%, 86.9%, 95.5%, and 94.5% respectively. The overall diagnostic sensitivity, specificity, positive predictive value, negative predivtive value, and accuracy of MDCT for determining liver metastasis was 74.1%, 99.7%, 83.3%, 99.5%, and 99.2% respectively; those for determining peritoneal metastasis was 54.5%, 99.3%, 87.1%, 96.4%, and 96.0%; and those for determining distant lymph node metastasis was 76.3%, 99.1%, 84.1%, 98.6%, and 97.8% respectively.

Conclusions: The clinical value of MDCT in the preoperative staging of gastric cancer is relatively high. Diagnostic laparoscopy is still needed in selecting patients with high risk of peritoneal metastasis to avoid unnecessary exploratory laparotomy, as a result of the relatively low sensitivity of MDCT for detecting peritoneal metastasis.

Keywords: Stomach neoplasms; tomography; X-ray computer; neoplasm staging

Cite this abstract as: Yan C, Zhu ZG, Yan M, Chen J, Xiang M, Chen MM, Zhang H, Liu BY, Lin YZ. Value of multidetector-row CT in the preoperative staging of gastric cancer: a single-center and large-scale study. Transl Gastrointest Cancer 2013;2(S1):AB54. doi: 10.3978/j.issn.2224-4778.2013.s054