67. The number, the ratio of positive lymph nodes or log odds, which is the most suitable classification for gastric cancer with lymph nodes were retrieved no less than 15?
Original Article

67. The number, the ratio of positive lymph nodes or log odds, which is the most suitable classification for gastric cancer with lymph nodes were retrieved no less than 15?

Hong-Gen Liu

Department of Gastrointestinal Oncology Surgery, Key Lab of Cancer Treatment and Prevention, Tianjin Cancer Hospital, Tianjin Medical University, Tianjin 300060, China


Objective: The aim of the current study was to investigate the Numbers (N classification), the Ratio of Positive Lymph Nodes (rN classification), Log Odds (LODDS classification), which is the most suitable classification for gastric cancer when lymph nodes are retrieved no less than 15.
Methods: From January 2001 to December 2007 Clinicpathologic and prognostic data of 561 gastric cancer patients were retrospectively studied. The log-rank statistics, Cox’s proportional hazards model and ROC curves were used. Results: Univariate and three-step multivariate analyses identified that rN classification was a significant prognostic factor and rN classification was superior to both the N and LODDS classifications when lymph nodes are retrieved no less than 15. For patients in each rN classifications, prognosis was homologous between those in different N or LODDS classifications. rN classifications has more potential in minimizing stage migration than N classification. Furthermore ROC curves show rN classification was better than the other two classifications.
Conclusions: For patients with gastric cancer when the numbers of lymph nodes are retrieved no less than 15 in operation, the rN classification is more suitable than N and LODDS classifications for prognostic assessment.

Key words

Log odds, gastric cancer; lymph nodes

DOI: 10.3978/j.issn.2224-4778.2012.s067